Stem Cell Therapy

What are Stem Cell?

They are undifferentiated cells without a specific function other than the ability to turn into cells with specialized functions based on the body’s requirements, but not all stem cells can change to just any cell and perform just any function.

Source of stem cell therapy?

They may come from various sources, such as adipose or fat tissue, placental tissue, umbilical cord tissue, or bone marrow.

How are Stem cells administered?

They can be administered intravenously (IV), directly into the spinal cord through intrathecal injection, directly injected into the affected areas, such as the face, hips, knees, or hands.

Mesenchymal Stem Cells (MSCs)

Mesenchymal stem cells (MSCs) originate from the connective tissue or stroma. around your body’s organs and tissues. Scientists have explored using them for new body tissues due to their ability to differentiate into any cell type.

Embryonic Stem Cells

After a sperm fertilizes an egg, an embryo is formed into a ball of cells called a blastocyst. A blastocyst already contains stem cells called embryonic stem cells at 4 to 5 days old. Embryonic stem cells can turn into any cells from blood to skin cells as needed. Since embryos have a lot of development to go through, embryonic stem cells are able to differentiate into more cells than adult ones.

What is the controversy?

Human Embryonic Stem Cells may NOT be used and are NEVER used in any clinical setting, because it would destroy the blastocyst and thus a potential embryo. However, you may have heard of their use in some research settings from extra embryos from in vitro fertilization (IVF), which is highly controversial.

Source of cells for stem cell therapy?

Regenerative Medicine requires a reliable source of cell therapy in addition to biomaterial scaffolds and cytokine growith factors.

UMBILICAL CORD CELLS – have been found to carry markers CD 34+ CD 45+ CD 73 and CD 90, which suggest the presence of stem cells, including HPC and MSCs, respectively in the product. These cells release Growth factors which play a critical role in repair. GF2 is involved in many aspects of growth, development and healing. It also plays a role in bone and cartilage formation, which may be beneficial for orthopedic injuries. The protein and IL-1, which is present in abundance in this product is a natural inhibitor of the pro-inflammatory state and plays a role in immuno-modulation inhibition of the pro inflammatory TNF– alpha. IL-1ra release from the cells may be critical in its ability to control the inflammatory response, which occurs, following disease and trauma states. The VEGF is a signaling protein produced by the stem cells that stimulate and vasogenesis and helps to restore oxygenation to tissues and cells when blood supplies in it is inadequate, vital in healing and repair. Other growth factors mediate cell, survival, migration, and proliferation.

ADIPOSE TISSUE – adipose tissue represents an abundant and accessible source of adult cells with the ability to differentiate along multiple lineage pathways. Stem cell therapy cells derived from adipose tissue are multipotent and promising for a range of therapeutic applications.

PERIPHERAL BLOOD – about 10,000 stem cell therapy cells can be obtained and of these 50% can become mesenchymal stem cell therapy cells.

BONE MARROW – approximately 50,000 NCP can be obtained from the sample. 50% become mesenchymal stem cell therapy cells.

LIPID TISSUES – about 5 to 10 million ASC can come from the sample. 90% become mesenchymal stem cell therapy cells.

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